Vaping may raise cancer and heart disease risk, study suggests

01 February, 2018, 00:55 | Author: Inez Murphy
  • Vaping and e-cigarettes have gained considerable popularity as a less harmful alternative to traditional cigarettes

That might be even harder to do for e-cigarettes, since many users are either former or current smokers, and there'd be no easy way to tell where the cancer risk from smoking ends and the cancer risk from vaping begins. Results also demonstrated that vaping may be less addictive than smoking, as shown by longer delay times in the morning before vaping and a trend of reducing nicotine levels in e-cigarette liquid over time. Perhaps unsurprisingly though, it's the nicotine that causes the damage, while solvents themselves do not appear to cause DNA damage at all.

The scientists did note that "many of these e-cig smokers [who] have taken up the e-cig smoking habit are not necessarily doing it for the objective of quitting TS (tobacco smoking), rather, it is because they are assuming that e-cig smoking is safe" in their writing.

They also pointed out that cardiovascular disease, not cancer, is the greatest risk of premature death for a smoker, causing nearly half of premature deaths (48%) among smokers. Mice subjected to the equivalent of "light" e-cigarette smoking for 10 years (12 weeks in reality) suffered DNA damage to their bladders, hearts and lungs, in addition to limiting both DNA fix and lung proteins. The popularity of e-cigarettes decreases with age and is used more by teenagers and young adults. This amounted to what Hajek called "extremely large doses of nicotine".

Researchers report the DNA-damaging potential of E-cigarette smoke (ECS).

In the tests, mice breathing the e-cigarette vapour showed greater damage to their DNA in the heart, lungs and bladder, as well as being more likely to develop tumours compared to the control group of mice breathing filtered air. Natural DNA fix mechanisms were also suppressed in the mice exposed to the smoke. Details of the study are reported in the journal Proceedings of the National Academy of Sciences.

The tests were also carried on cultured human lung and bladder were found to have similar results. "We need to actively address these misperceptions about the risks of e-cigarettes, which can have real-world consequences for public health", Kaleechurn said.

Tang could not say whether e-cigarettes are still safer than traditional cigarettes, which contain thousands of harmful chemicals produced by burning tobacco.

"Up to two-thirds of long term smokers will die due to their addiction, but e-cigarettes don't contain tobacco".



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